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Download e-book for iPad: An Illustrated Pocketbook of Hypertension by Peter F. Semple

By Peter F. Semple

This useful sized pocket reference is designed to supply knowledgeable yet concise evaluation of the main parts of high blood pressure that might be of curiosity and relevance to clinicians. hugely illustrated in complete colour, with lucid textual content and hard self-assessment questions, the e-book can be of curiosity to citizens and different physicians frightened to replace their wisdom during this box.

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Taurine has been shown in a number of studies to diminish the damaging effects of ER stress. In a recent study on C. elegans exposed to the ER stress inducer tunicamycin it was found that taurine treatment was able to enhance longevity, mobility, and fecundity of the organism (Kim et al. 2010). 8 25 Conclusion In summary, taurine exerts its neuroprotective function minimally through its action at both the mitochondrial and ER levels by decreasing the expression and/or the activity of Grp78, caspase-12, CHOP, ROS levels, Bim, and cytochrome C release and increasing the level of Bcl-2.

In our study, the rats fed with taurine at approximately 400–500 mg taurine/kg body weight/day for 4 weeks did not change their locomotor activity or average speed in OF. Therefore, OF was not influenced by the ability of taurine to improve physical endurance. Our FS data were also not influenced by this ability of taurine because taurine improves physical 3 Antidepressant-Like Effect of Chronic Taurine Administration… 37 endurance with a dose less than that of a taurine-supplemented diet (Miyazaki et al.

1 Introduction Taurine, or 2-aminoethanesulfonic acid, is a sulfonic acid which is derived from cysteine and it is one of the few naturally occurring sulfonic acids. Taurine is widely distributed in animal tissues and one of the most abundant amino acid in mammals. Taurine plays several crucial roles including modulation of calcium signaling, osmoregulation, and membrane stabilization. However, despite extensive study, the mechanisms of action of taurine are not well understood. Based on past studies taurine has appeared as a promising agent for treating several neurological disorders including Alzheimer’s disease, Huntington’s disease, and stroke because of its ability to prevent apoptosis and its capacity to act as an antioxidant.

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An Illustrated Pocketbook of Hypertension by Peter F. Semple


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